DPN has long been considered “progressive and irreversible”.

It is also the main cause of foot ulcers, infections, and amputations. Conclusions: The nerve conduit could further improve the efficacy of peripheral nerve decompression microsurgery in the treatment of DPN.ĭiabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes, with an incidence rate of as high as 50–60%. There was a significant difference in the TCSS scores between the nerve conduit group and the conventional surgery group ( p < 0.05). The TCSS score in the two surgical groups was significantly higher than that in the control group ( p < 0.01). For the 2-PD test, there was a statistically significant difference between the two surgical groups ( p < 0.05). The postoperative nerve conduction velocity (NCV) in the two surgical groups was significantly higher than that before the surgery, and the difference between the nerve conduit group and the conventional surgery group was statistically significant ( p < 0.05). Results: The patients’ symptoms in the nerve conduit group were relieved to varying degrees, and the relief rate reached 90.9% the treatment efficacy was higher than that in the other groups. Two weeks before surgery and 6 months after surgery, patients in each group were clinically tested using the visual analog scale (VAS) score, neurophysiological test, Toronto clinical scoring system (TCSS) score, and two-point discrimination (2-PD) test. Methods: A total of 69 patients with DPN were recruited and randomly divided into three groups: the nerve conduit group, conventional surgery group, and control group. In this study, a nerve conduit was used in the peripheral nerve decompression microsurgery to prevent postoperative adhesions, and the role of the nerve conduit in surgical nerve decompression was explored. However, postoperative tissue adhesion will produce new pressure on the nerves, affecting the surgical efficacy.

Background: Peripheral nerve decompression microsurgery can relieve nerve entrapment and improve the symptoms of DPN.

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